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Long-Term Weight Management Requires More Than a Prescription

Dr. Timothy Law, Chief Medical Officer, Vice President, Integrative Care Delivery Highmark Inc.

Obesity is one of America's most daunting public health challenges. It's a complex condition that involves everything from our food choices and physical activity to family history to the conditions in which we are born, grow up, live, work and age. Being obese can increase a person's risk factors for serious health issues like high blood pressure, heart disease, diabetes and cancer. And it's a growing problem, with more than 40% of U.S. adults having obesity, according to the Centers for Disease Control and Prevention. Twenty years ago, about 30% of U.S. adults were obese.

It's no wonder, then, that Americans are searching for effective weight management solutions. Nearly half of U.S. adults are interested in taking a weight loss drug, according to the Kaiser Family Foundation. A new class of weight loss medications — called glucagon-like peptide-1 (GLP-1) receptor agonists — holds promise. These medications, which were initially developed to treat diabetes, mimic a hormone that makes us feel fuller and eat less.

Discussions on GLP-1s are everywhere — in the news, on social media, at the dinner table. They're sometimes billed as a miracle drug. But the reality is that effective, long-term weight management is more complicated than that.

Weight Loss Drugs: Hype vs. Reality

If people take a prescription medication, we want it to be safe and effective. When it comes to weight loss drugs, a significant portion of patients do not remain on the medications long enough to realize the hoped-for health benefits.

For example, a May 2024 issue brief released by Blue Health Intelligence (BHI) for the Blue Cross Blue Shield Association evaluated members with employer-based Blue Cross Blue Shield health insurance coverage and found that about 60% of those taking GLP-1 medications for weight loss discontinued use before seeing a clinical benefit. The study followed nearly 170,000 members over the span of a decade.

There are serious issues with patients discontinuing treatment due to side effects like gastrointestinal problems. During the first four weeks of treatment, when patients are gradually having their medication dosage increased, the BHI report noted that more than 30% stopped taking the drug altogether. There are also supply shortages of these medications, which has at times made them difficult to find for patients prescribed GLP-1s for diabetes.

A Comprehensive Approach to Weight Management

At Highmark, we view weight loss medications, including GLP-1s, as part of a multi-faceted weight management program. A health plan member's chances of successfully managing weight are greatly improved when paired with lifestyle changes such as diet and exercise and side-effect management from a health care provider with expertise in managing patients with obesity. Highmark members have access to a variety of weight management and health improvement benefits, including nutrition counseling, fitness programs and personalized health coaching.

Like health insurers across the U.S., we regularly evaluate our prescription medication policies, including for weight loss medications. Our coverage policies are consistent with medical policy, state and federal mandates, and the evolving research on the effectiveness and safety of weight loss medications, including GLP-1s. We will continue to follow the clinical and real-world outcomes on weight loss medications and other interventions to provide our members with effective, safe and sustainable weight management solutions.

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Highmark Health and its subsidiaries and affiliates comprise a national blended health organization that employs more than 42,000 people and serves millions of Americans across the country.

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